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calculus, but not against the more destructive periodontal disease. There is also the risk of fractured teeth.
Nitric oxide (NO), an important inflammatory mediator, is increased in human periodontitis and agents blocking the production of NO or its effects might be therapeutically valuable. Lactobacillus brevis (L brevis), is a probiotic bacteria which contains high levels of arginine deiminiase (AD). High levels of AD inhibit NO generation by competing with NO synthase for the arginine substrate. In humans topical application of probiotics containing
L brevis decreased inflammatory mediators involved
in periodontitis. Preliminary results of topical L brevis CD2 in dogs showed reduced of gingival inflammatory infiltrates13.
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3. Gawor J.P., Reiter A.M., Jodkowska K, et al. Influence of diet on oral health in cats and dogs. Journal of Nutrition 2006; 136:2021S-2023S.
4. Boyce E.N., Logan E.I. Oral health assessment in dogs: Study design and results. Journal of Veterinary Dentistry 1994; 11: 64-74.
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7. Stookey G.K., Warrick J.M., Miller L.L. Sodium hexametaphosphate reduces calculus formation in dogs. American Journal of Veterinary Research 1995; 56: 913-918.
8. Logan E.I., Wiggs R.B., Schert D., and Cleland P. Periodontal disease. In Small Animal Clinical Nutrition 5th Edn. Editors: Hand MS, Thatcher CD, Remillard RL, Roudebush P and Novotny BJ. 2010. Mark Morris Institute, Topeka, Kansas, US. pp 989 – 1001.
9. Robinson J.G.A. and Gorrel C. The oral status of a pack of foxhounds fed a “natural” diet. In: Proceedings. World Veterinary Dental Congress, 1997. Birmingham, UK: 35-37.
10. Steenkamp G and Gorrell C. Oral and dental conditions in adult African wild dog skulls: a preliminary result. Journal of Veterinary Dentistry 1999; 16(2):913- 918.
11. Verstraete F.J., van Aarde R.J., Nieuwoudt B.A., et al. The dental pathology of feral cats on Marion Island; part II: periodontitis, external odontoclastic resorption lesions and mandibular thickening. Journal of Comparative Pathology 1996; 115(3):283-297.
12. Clarke D.R. and Cameron A. Relationship between diet, dental calculus and periodontal disease in domestic and feral cats in Australia. Australian Veterinary Journal 1996; 76(10):690-693.
13. Vullo C. Lactobacillus brevis CD2 and odontostomatological diseases. Probiotics in veterinary medicine - an update and perspectives. The Sivoy Study The Sivoy Study Group, Rome 17 March 2014, Abstract
An Urban Experience

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