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An Urban Experience
included it in every case after surgery. When asked what adjuvant therapy one preferred after surgical excision, 73% answered immunotherapy, 16% chemotherapy, 7% NSAIDS and 4% radiation therapy.
MM Vaccine
When asked if the audience felt that the current available melanoma vaccine was effective, 58% answered yes. When asked if they use the vaccine, 84% of the audience said yes. Additionally 55% used it for stage 4 patients. The question, how many vaccines should you give was answered by 38% as many as you can give, >4 doses by 36% and 4 doses by 21 percent. Should stage 1-2 patient receive adjuvant immunotherapy, 87 percent said yes.
Chemotherapy
Chemotherapy was only used in 35% of cases, of which carboplatin was most popular. Seventy six percent gives 4-6 doses of carboplatin if used.
Other questions
If you would find a oral mass during a dental procedure would you proceed with the dental procedure after biopsy of the mass, was answered in the positive by 50% of the audience.
Concerning tong amputations: The amount of tongue you can amputate in dogs with still have the ability to eat was answered as follows:
Discussion
A major disclaimer of this study was that the study population was extremely skewed towards a surgical oncology attendee at the VSSO symposium, so all data interpretation should be interpreted with caution. In general, the results were very similar to the pre-event enquiry done by 88 VSSO members (data not shown).
As general guidelines for COMM one could extrapolate
• Distant metastases and lymph node involvement are the most important prognostic determinants
• Most people aspirate at least one lymph node before surgery routinely and also remove the ipsilateral lymphnode during surgery
• CT of the chest is the preferred technique for thoracic and abdominal ultrasound for evaluation of the presence of metastases
• COMM should be excised with wide or radical margins and marginal cuts should be redone
• The role of chemo- or radiation therapy is unclear
at the moment, radiation therapy is most commonly used for tumors that can not be cut and of the chemotherapy options, at least 4 doses of carboplatin is the most used
• The MM vaccine is used often by this audience, also for stage 1-2 patients, but not everyone is convinced of it’s efficacy. At least 4 doses are preferred.
• There are strict differences between dogs an cats of how much tongue you can remove without affecting the ability to eat or drink.
1. Smith, S. H., Goldschmidt, M. H. & McManus, P. M. A comparative review of melanocytic neoplasms. Vet. Pathol. 39, 651-678 (2002).
2. Bergman, P. J. Canine Oral Melanoma. Clin. Tech. Small Anim. Pract. 22, 55- 60 (2007).
3. Modiano, J. F., Ritt, M. G. & Wojcieszyn, J. The molecular basis of canine melanoma: pathogenesis and trends in diagnosis and therapy. J. Vet. Intern. Med. 13, 163-174 (1999).
4. Manley, C. A. et al. Xenogeneic Murine Tyrosinase DNA Vaccine for Malignant Melanoma of the Digit of Dogs. J. Vet. Intern. Med. 25, 94-99 (2011).
5. Bergman, P. J. et al. Long-term survival of dogs with advanced malignant melanoma after DNA vaccination with xenogeneic human tyrosinase: A phase I trial. Clinical Cancer Research 9, 1284-1290 (2003)
 Percentage of amputation
 n=
  Dog
  Cat
  100
   15
  26.80%
  2.00%
  80
   28
  50.00%
  10.00%
  60
   9
  16.10%
  8.00%
 50
 4
   7.10%
   80.00%
  42ND WORLD SMALL ANIMAL VETERINARY ASSOCIATION CONGRESS AND FECAVA 23RD EUROCONGRESS
  



















































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