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528
An Urban Experience
Withholding empiric antimicrobial treatment for 24 hours while awaiting the result of point of care culture is an option to consider in many cases of canine sporadic cystitis. Palliative treatment with non-steroidal anti- in ammatory drugs (NSAIDS) can be initiated, where no contraindications are present.
9.
10.
Choice of antibiotic treatment should ideally be based on susceptibility data. This is however rarely rapidly available, and initiation of empiric treatment of non- recurrent cases is justi ed if signi cant bacteriuria is found on in-house QBC. Amoxicillin and potentiated sulfonamides (TMS) are both accumulating in high concentrations in urine and are therefore generally
good  rst line agents towards the most common uro- pathogens. Resistance-rates do however vary across Europe (6), and (when available) local/regional guidelines should be consulted to guide empiric choice of antibiotic class.
There is very sparse evidence with regard to optimal duration of treatment in companion animal UTI including canine sporadic cystitis (7). Recent randomized controlled studies suggest that short term (3 days) treatment of TMS (8) and high dose enro oxacin (9) is non-inferior to long term (7-14 days) treatment with beta- lactams in treating canine sporadic cystitis. Short term treatment with amoxicillin has not been investigated in dogs, but in people a 3-5 days course of pivmecillinam
is considered adequate (10). The bene ts of short
term treatment include not only reduced antimicrobial resistance selection pressure, but also reduced adverse effects, increased compliance and reduced costs.
Monitoring of bacteriuria during or after completion of therapy is not advised unless clinical signs persist or recur.
Litterature
1. Sørensen TM, Jensen AB, Damborg P, Bjørnvad CR, Guardabassi L, Jessen LR. Evaluation of different sampling methods and criteria for diagnosing canine urinary tract infection by quantitative bacterial culture. The Veterinary Journal. 2016;216:168-73.
2. T.M. Soerensen, C.R. Bjornvad, K.M. Hoelmkjaer, L. Guardabassi, L. Bjerrum, Jessen LR. Research Communications of the 26th ECVIM-CA Congress. Diagnostic Work-Up Does Not Affect Appropriate Antibiotic Prescription In Dogs With Suspected Urinary Tract Infection - An Observational Study In Danish Small Animal Practices. J Vet Intern Med. 2017;31(1):217.
3. Jacob ME, Crowell MD, Fauls MB, Grif th EH, Ferris KK. Diagnostic accuracy of a rapid immunoassay for point of-care detection of urinary tract infection in dogs. American journal of veterinary research. 2016;77(2):162-6.
4. Swenson CL, Boisvert AM, Gibbons-Burgener SN, Kruger JM. Evaluation of modi ed Wright-staining of dried urinary sediment as a method for accurate detection of bacteriuria in cats. Veterinary clinical pathology / American Society for Veterinary Clinical Pathology. 2011;40(2):256-64.
5. Swenson CL, Boisvert AM, Kruger JM, Gibbons-Burgener SN. Evaluation of modi ed Wright-staining of urine sediment as a method for accurate detection of bacteriuria in dogs. Journal of the American Veterinary Medical Association. 2004;224(8):1282-9.
6. Marques C, Gama LT, Belas A, Bergstrom K, Beurlet S, Briend-Marchal A, et al. European multicenter study on antimicrobial resistance in bacteria isolated from companion animal urinary tract infections. BMC Vet Res. 2016;12(1):213.
7. 8.
Jessen LR, Sorensen TM, Bjornvad CR, Nielsen SS, Guardabassi L. Effect of antibiotic treatment in canine and feline urinary tract infections: a systematic review. Veterinary journal (London, England: 1997). 2015;203(3):270-7.
Clare S, Hartmann FA, Jooss M, Bachar E, Wong YY, Trepanier LA,
et al. Short- and long-term cure rates of short-duration trimethoprim- sulfamethoxazole treatment in female dogs with uncomplicated bacterial cystitis. Journal of veterinary internal medicine / American College of Veterinary Internal Medicine. 2014;28(3):818-26.
Westropp JL, Sykes JE, Irom S, Daniels JB, Smith A, Keil D, et al. Evaluation of the ef cacy and safety of high dose short duration enro oxacin treatment regimen for uncomplicated urinary tract infections in dogs. Journal of veterinary internal medicine / American College of Veterinary Internal Medicine. 2012;26(3):506-12.
Grabe M, Bartoletti R, Bjerklund-Johansen TE, Cek HM, Pickad RS, Tenke P, et al. Guidelines on Urological Infections. EAU, European Association of Urology; 2014.
42ND WORLD SMALL ANIMAL VETERINARY ASSOCIATION CONGRESS AND FECAVA 23RD EUROCONGRESS


































































































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