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An Urban Experience
be complicated, as the veterinarian should try to avoid broad-spectrum drugs, prioritize drugs licensed for the infection and patient, prioritize drugs that concentrate at the site of infection, avoid drugs with potential side effects, and consider the optimal administration route, dose, and length of treatment.
In conclusion, AST is useful for guiding antimicrobial choice and for detection of important resistance phenotypes such as ESBLs. However, veterinarians should strongly consider using external laboratories
for AST unless they stick meticulously to approved standards specifying methodology and criteria for interpretation. Even after a properly performed AST,
it may be challenging to choose an antibiotic, and it
is therefore recommended that veterinarians consult microbiologists or national treatment guidelines when in doubt.
References.
1. Guardabassi L, Prescott JF. Antimicrobial stewardship in small animal veterinary practice: from theory to practice. Veterinary Clinics of North America: Small Animal Practice 2015, 45(2):361-76.
2. Wieler LH, Ewers C, Guenther S, Walther B, Lübke-Becker A. Methicillin- resistant staphylococci (MRS) and extended-spectrum beta-lactamases (ESBL)- producing Enterobacteriaceae in companion animals: nosocomial infections as one reason for the rising prevalence of these potential zoonotic pathogens in clinical samples. International Journal of Medical Microbiology 2011, 301(8):635- 641.
3. Weese JS, Giguère S, Guardabassi L, Morley PS, Papich M, Ricciuto DR, Sykes JE. ACVIM consensus statement on therapeutic antimicrobial use in animals and antimicrobial resistance.Journal of Veterinary Internal Medicine. 2015, 29(2):487-98.
4. Clinical Laboratory Standards Institute (CLSI). Performance standards for antimicrobial disk and dilution susceptibility tests for bacteria isolated from animals; second informational supplement. CLSI document VET01S2. Wayne: CLSI; 2013.
42ND WORLD SMALL ANIMAL VETERINARY ASSOCIATION CONGRESS AND FECAVA 23RD EUROCONGRESS


































































































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