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compared to 40% of cats on the same diet in a dry formulation, experienced recurrent clinical signs. In cats with obstructive FIC, the current recommendation is to feed a moderately acidifying diet with high water content to prevent formation of struvite crystals, which are the most commonly identi ed crystals in urethral plugs.
A more recent study of cats with non-obstructive FIC revealed a signi cantly lower rate of recurrent clinical episodes and a lower number of days with clinical signs by feeding a diet with an altered fatty acid pro le and increased amounts of antioxidants (13).
1. Treutlein G, Dorsch R, Euler KN, Hauck SM, Amann B, Hartmann K, et al. Novel potential interacting partners of  bronectin in spontaneous animal model of interstitial cystitis. PLoS One. 2012;7(12):e51391.
2. Dorsch R, Zellner F, Schulz B, Sauter-Louis C, Hartmann K. Evaluation of meloxicam for the treatment of obstructive feline idiopathic cystitis. J Feline Med Surg. 2015.
3. Wu CH, Buf ngton CA, Fraser MO, Westropp JL. Urodynamic evaluation of female cats with idiopathic cystitis. Am J Vet Res. 2011;72(4):578-82.
4. Delille M, Frohlich L, Muller RS, Hartmann K, Dorsch R. Ef cacy of intravesical pentosan polysulfate sodium in cats with obstructive feline idiopathic cystitis. J Feline Med Surg. 2015.
5. Bradley AM, Lappin MR. Intravesical glycosaminoglycans for obstructive feline idiopathic cystitis: a pilot study. J Feline Med Surg. 2014;16(6):504-6.
6. Hetrick PF, Davidow EB. Initial treatment factors associated with feline urethral obstruction recurrence rate: 192 cases (2004-2010). J Am Vet Med Assoc. 2013;243(4):512-9.
7. Wallius BM, Tidholm AE. Use of pentosan polysulphate in cats with idiopathic, non-obstructive lower urinary tract disease: a double-blind, randomised, placebo-controlled trial. J Feline Med Surg. 2009;11(6):409-12.
8. Gunn-Moore DA, Shenoy CM. Oral glucosamine and the management of feline idiopathic cystitis. J Feline Med Surg. 2004;6(4):219-25.
9. Chew DJ, Bartges JW, Adams LG, Kruger JM, Buf ngton CAT. Randomized, Placebo-Controlled Clinical Trial of Pentosan Polysulfate Sodium for Treatment of Feline Interstitial (Idiopathic) Cystitis. ACVIM 2009.
10. Osborne CA, Kruger JM, Lulich JP, Johnston GR, Polzin DJ, Ulrich LK, et al. Prednisolone therapy of idiopathic feline lower urinary tract disease: a double- blind clinical study. Vet Clin North Am Small Anim Pract. 1996;26(3):563-9.
11. Zezza L, Reusch CE, Gerber B. Intravesical application of lidocaine and sodium bicarbonate in the treatment of obstructive idiopathic lower urinary tract disease in cats. J Vet Intern Med. 2012;26(3):526-31.
Markwell PJ, Buf ngton CA, Chew DJ, Kendall MS, Harte JG, DiBartola SP. Clinical evaluation of commercially available urinary acidi cation diets
in the management of idiopathic cystitis in cats. J Am Vet Med Assoc. 1999;214(3):361-5.
12. Markwell PJ, Buf ngton CA, Chew DJ, Kendall MS, Harte JG, DiBartola SP. Clinical evaluation of commercially available urinary acidi cation diets in the management of idiopathic cystitis in cats. J Am Vet Med Assoc. 1999;214(3):361-5.
13. Lulich JP, Kruger JM, Macleay JM, Merrills JM, Paetau-Robinson I, Albasan H, et al. Ef cacy of two commercially available, low-magnesium, urine-acidifying dry foods for the dissolution of struvite uroliths in cats. J Am Vet Med Assoc. 2013;243(8):1147-53.
An Urban Experience
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