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An Urban Experience
for complicated UTI. This recommendation is based
on expert opinions. There are no prospective studies evaluating the duration of antimicrobial treatment of
feline UTI.In cats with indwelling urinary catheters, prophylactic antimicrobial therapy for prevention of UTI
is never indicated. A urine sample (ideally collected by cystocentesis) should be submitted for culture at the time of catheter removal and possible infection treated based on results of culture/susceptibility testing. So far, the signi cance of subclinical bacteriuria in dogs and cats is not fully understood, and it is not known whether treatment of cats with asymptomatic bacteriuria is always bene cial. In a recent study, 67 nonazotemic cats > 7 years had urine cultures performed on up to 5 occasions over a three-year period (11). The incidence of subclinical bacteriuria varied between 10 and 13%. Cats with positive urine culture were not treated with antimicrobials. An adverse association between subclinical bacteriura and survival was not identi ed in this study population. Asymptomatic bacteriuria is a common  nding in healthy women and in women and men with comorbidities. Several randomized clinical trials have identi ed no bene ts of antimicrobial treatment in asymptomatic individuals. It is, however, not possible to extrapolate these results to cats and dogs. So far, there are no prospective studies in cats with subclinical bacteriuria. Current guidelines recommend considering treatment
for asymptomatic bacteriuria in patients at high risk of ascending or systemic infections, such as chronic kidney disease, systemic immunosuppression or diabetes mellitus.
1. Martinez-Ruzafa I, Kruger JM, Miller R, Swenson CL, Bolin CA, Kaneene JB. Clinical features and risk factors for development of urinary tract infections in cats. J Feline Med Surg. 2012;14(10):729- 40.
2. Weese JS, Blondeau JM, Boothe D, Breitschwerdt EB, Guardabassi L, Hillier A, et al. Antimicrobial use guidelines for treatment of urinary tract disease in dogs and cats: antimicrobial guidelines working group of the international society for companion animal infectious diseases. Vet Med Int. 2011;2011:1-9.
3. Swenson CL, Boisvert AM, Gibbons-Burgener SN, Kruger JM. Evaluation of modi ed Wright-staining of dried urinary sediment as a method for accurate detection of bacteriuria in cats. Vet Clin Pathol. 2011;40(2):256-64.
4. Litster A, Moss S, Platell J, Trott DJ. Occult bacterial lower urinary tract infections in cats-urinalysis and culture  ndings. Veterinary microbiology. 2009;136:130-4.
5. Mayer-Roenne B, Goldstein RE, Erb HN. Urinary tract infections in cats with hyperthyroidism, diabetes mellitus and chronic kidney disease. J Feline Med Surg. 2007;9(2):124-32.
6. White JD, Stevenson M, Malik R, Snow D, Norris JM. Urinary tract infections in cats with chronic kidney disease. J Feline Med Surg. 2013;15(6):459-65.
7. Bailiff NL, Nelson RW, Feldman EC, Westropp JL, Ling GV, Jang SS, et al. Frequency and risk factors for urinary tract infection in cats with diabetes mellitus. J Vet Intern Med. 2006;20(4):850-5.
8. Dorsch R, von Vopelius-Feldt C, Wolf G, Mueller RS, Straubinger RK, Hartmann K. Urinary tract infections in cats. Prevalence
of comorbidities and bacterial species, and determination of antimicrobial susceptibility to commonly used antimicrobial agents. Tierarztl Praxis (K). 2016;44(4):227-36.
9. Lund HS, Skogtun G, Sorum H, Eggertsdottir AV. Antimicrobial susceptibility in bacterial isolates from Norwegian cats with lower urinary tract disease. J Feline Med Surg. 2015;17(6):507-15.
10. Dorsch R, von Vopelius-Feldt C, Wolf G, Straubinger RK, Hartmann K. Feline urinary tract pathogens: prevalence of bacterial species and antimicrobial resistance over a 10-year period. Vet Rec. 2015;176(8):201.
11. White JD, Cave NJ, Grinberg A, Thomas DG, Heuer C. Subclinical Bacteriuria in Older Cats and its Association with Survival. J Vet Intern Med. 2016;30(6):1824-9.

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