Page 723 - ONLINE PROCEEDING BOOK WSAVA 2017
P. 723

WSVA7-0214 DIAGNOSTIC IMAGING
THE EFFECT OF AGE ON THE THICKNESS OF THE INTERTHALAMIC ADHESION OF DOMESTIC CATS
V.R. Babicsak1, A.V. Klein2, M.H. Tsunemi3, L.C. Vulcano1
1São Paulo State University, Department of Animal Reproduction and Veterinary Radiology, Botucatu, Brazil 2São Paulo State University, Departament of Veterinary Surgery and Anesthesiology, Botucatu, Brazil
3São Paulo State University, Department of Biostatistics, Botucatu, Brazil
Introduction
During aging, it is reported that dogs suffer a decrease in the thickness of the interthalamic adhesion.
Objectives
The aim of this study was to identify whether the thickness of the interthalamic adhesion of healthy domestic cats reduces with increasing age.
Methods
WSVA7-0215 DIAGNOSTIC IMAGING
CORRELATION BETWEEN THICKNESS OF THE INTERTHALAMIC ADHESION AND CEREBRAL ATROPHY IN HEALTHY DOMESTIC CATS
V.R. Babicsak1, A.V. Klein2, M.H. Tsunemi3, L.C. Vulcano1
1São Paulo State University, Department of Animal Reproduction and Veterinary Radiology, Botucatu, Brazil 2São Paulo State University, Department of Veterinary Surgery and Anesthesiology, Botucatu, Brazil
3São Paulo State University, Department of Biostatistics, Botucatu, Brazil
Introduction
In dogs, the thickness of the interthalamic adhesion is considered an important marker for monitoring the progression of cerebral atrophy.
Objectives
The aim of this study was to determine whether the thickness of the interthalamic adhesion is a reliable predictor for the progression of cerebral atrophy in healthy domestic cats.
Methods
Brain MRI images of twelve adult (1-6 years), eleven mature (7-11 years) and ten geriatric (12 years of age or older) non- brachycephalic cats were obtained in this study. Thickness of the interthalamic adhesion was measured on transverse T1- and T2-weighted sequences and then, the average value was calculated. Cerebral volume was determined by manual delimitation of the cerebral surface on transverse T1-weighted images. Ventricle volumes (lateral and third ventricles) were subtracted from the cerebral volume, obtaining the volume of the cerebral parenchyma, which was corrected for the intracranial volume, posteriorly. Pearson test was used to obtain the correlation between the thickness of the interthalamic adhesion and percentage of the cerebral parenchyma volume by intracranial volume.
Results
Signi cant positive association was found between the thickness of the interthalamic adhesion and percentage of the cerebral parenchyma volume by intracranial volume. However, the correlation between these two variables was considered moderate (r=0.410) and not strong, as expected.
Conclusions
In conclusion, the results indicate that thickness of the interthalamic adhesion may predict the progression of cerebral atrophy in cats, however, it may not be the most reliable parameter to monitor cerebral atrophy in these animals.
Twelve adult (1-6 years), eleven mature (7-11 years)
and ten geriatric (12 years of age or older) non- brachycephalic cats were submitted to brain MRI studies. Thickness of the interthalamic adhesion was measured on transverse T1- and T2-weighted sequences and
an average value was obtained. Mean values of the thickness of the interthalamic adhesion of each group were compared by ANOVA test followed by Bonferroni multiple comparison test (p <0.05).
Results
The thickness of the interthalamic adhesion was signi cantly lower in geriatric cats in relation to the adults, corroborating the results found in dogs. The thickness was 0.28 mm lower in the mature cats than the adults and 0.32 mm lower in the geriatric animals in relation
to the mature cats. Considering the value calculated
for adults as basis, the thickness of the interthalamic adhesion reduced 5.81% between mature and adults and 6.43% between geriatric and mature groups, which imply in a decrease of 12.24% between geriatric and adult cats.
Conclusions
The results of this study demonstrate that the thickness of the interthalamic adhesion tends to decrease in domestic cats with age.
An Urban Experience
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